Michael Gale Selected Research

West Nile Fever

1/2021	Correlation of Regulatory T Cell Numbers with Disease Tolerance upon Virus Infection.
11/2019	Microglia in Memory Decline from Zika Virus and West Nile Virus Infection.
1/2019	STING is required for host defense against neuropathological West Nile virus infection.
1/2018	Splenic macrophages are required for protective innate immunity against West Nile virus.
1/2018	Interleukin-1β Signaling in Dendritic Cells Induces Antiviral Interferon Responses.
11/2017	Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization.
1/2017	MAVS Is Essential for Primary CD4+ T Cell Immunity but Not for Recall T Cell Responses following an Attenuated West Nile Virus Infection.
1/2017	Extrinsic MAVS signaling is critical for Treg maintenance of Foxp3 expression following acute flavivirus infection.
12/2016	Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.
8/2016	MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis.

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Michael Gale Research Topics

Disease

106	Infections 06/2022 - 04/2003
59	Virus Diseases (Viral Diseases) 12/2021 - 03/2002
28	West Nile Fever 01/2021 - 07/2004
14	COVID-19 06/2022 - 01/2020
13	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2021 - 02/2007
11	Inflammation (Inflammations) 12/2021 - 01/2008
9	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2002
6	HIV Infections (HIV Infection) 01/2022 - 09/2009
6	RNA Virus Infections 01/2019 - 01/2007
6	Chronic Hepatitis C 01/2015 - 01/2008
6	Melanoma (Melanoma, Malignant) 10/2014 - 09/2005
5	Neoplasms (Cancer) 01/2022 - 10/2006
5	Bites and Stings (Sting) 01/2020 - 01/2012
5	Hepatitis C 08/2014 - 10/2004
4	Liver Diseases (Liver Disease) 01/2021 - 03/2003
3	Human Influenza (Influenza) 01/2020 - 10/2012
3	Encephalitis (Encephalitis, Rasmussen) 01/2019 - 04/2013
3	Zika Virus Infection 01/2019 - 01/2018
3	Persistent Infection 08/2011 - 01/2002
2	Communicable Diseases (Infectious Diseases) 01/2020 - 02/2011
2	Flavivirus Infections 01/2020 - 01/2017
2	Fibrosis (Cirrhosis) 01/2018 - 04/2005
2	Autoimmune Diseases (Autoimmune Disease) 07/2017 - 01/2012
2	Heart Failure 01/2015 - 06/2014
1	Hirschsprung Disease (Hirschsprung's Disease) 07/2022
1	Body Weight (Weight, Body) 06/2022
1	Bacterial Vaginosis 01/2022
1	Critical Illness (Critically Ill) 12/2021
1	Tuberculosis (Tuberculoses) 01/2021
1	Dysbiosis 01/2021
1	Necrosis 03/2020
1	Abdominal Aortic Aneurysm 03/2020
1	Endoleak 03/2020

Drug/Important Bio-Agent (IBA)

68	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2002
47	InterferonsIBA 01/2022 - 01/2002
26	Proteins (Proteins, Gene)FDA Link 06/2022 - 01/2002
25	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2005
20	CytokinesIBA 01/2020 - 01/2008
15	VaccinesIBA 06/2022 - 02/2013
14	Interferon Type IIBA 01/2020 - 01/2008
14	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2018 - 02/2007
13	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2019 - 04/2005
12	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 02/2014 - 07/2004
10	Pattern Recognition ReceptorsIBA 01/2019 - 12/2008
10	LigandsIBA 01/2018 - 02/2005
9	Viral RNAIBA 01/2021 - 04/2002
9	InflammasomesIBA 01/2018 - 04/2009
9	Interferon-betaIBA 01/2018 - 07/2004
8	Transcription Factors (Transcription Factor)IBA 01/2019 - 02/2005
8	RNA Helicases (RNA Helicase)IBA 01/2019 - 04/2005
8	Interferon-alpha (Interferon Alfa)IBA 04/2013 - 10/2004
7	Phosphotransferases (Kinase)IBA 01/2020 - 03/2002
7	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 02/2005
6	Interferon Regulatory FactorsIBA 01/2021 - 09/2008
6	Interferon LambdaIBA 01/2019 - 04/2015
6	Nucleic AcidsIBA 01/2018 - 02/2007
6	Double-Stranded RNA (RNA, Double Stranded)IBA 10/2015 - 04/2002
6	ChemokinesIBA 06/2015 - 02/2010
5	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2016
4	AntigensIBA 12/2021 - 09/2011
4	Biological ProductsIBA 08/2020 - 01/2008
4	Small Interfering RNA (siRNA)IBA 06/2013 - 04/2005
4	NF-kappa B (NF-kB)IBA 04/2007 - 02/2005
3	Monoclonal AntibodiesIBA 07/2022 - 02/2013
3	Pharmaceutical PreparationsIBA 01/2020 - 01/2015
3	AntibodiesIBA 10/2019 - 07/2011
3	2-5A-dependent ribonuclease (RNase L)IBA 04/2015 - 07/2006
3	Toll-Like Receptor 3IBA 02/2014 - 04/2005
3	Peptide Hydrolases (Proteases)FDA Link 08/2011 - 05/2003
3	Ribavirin (Virazole)FDA LinkGeneric 09/2009 - 01/2008
2	Metronidazole (Metric)FDA LinkGeneric 01/2022 - 01/2015
2	Complement System Proteins (Complement)IBA 01/2020 - 01/2012
2	Antiviral Restriction FactorsIBA 12/2019 - 11/2016
2	NucleotidesIBA 01/2019 - 10/2014
2	Immunoglobulin G (IgG)IBA 01/2019 - 11/2017
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2018 - 01/2012
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2017
2	Interleukin-18 (Interleukin 18)IBA 01/2018 - 10/2014
2	MicroRNAs (MicroRNA)IBA 12/2016 - 01/2014
2	Poly UIBA 11/2015 - 02/2014
2	Poly I-CIBA 10/2014 - 04/2005
2	Messenger RNA (mRNA)IBA 01/2014 - 01/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2012 - 05/2008
1	Myelin P0 Protein (Myelin Protein Zero)IBA 07/2022
1	COVID-19 VaccinesIBA 06/2022
1	PolyestersIBA 04/2022
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022
1	Neutralizing AntibodiesIBA 01/2022
1	Peptides (Polypeptides)IBA 12/2021
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 12/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Granzymes (Granzyme)IBA 01/2021
1	InterleukinsIBA 01/2021
1	nuclear pore complex protein 98IBA 01/2021

Therapy/Procedure

21	Therapeutics 12/2021 - 04/2003
2	Aftercare (After-Treatment) 01/2021 - 02/2013
2	Highly Active Antiretroviral Therapy (HAART) 01/2021 - 01/2018
1	Transplantation 01/2022
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2022
1	Endovascular Aneurysm Repair 03/2020